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崙棫戝妛朄恖丗帬夑堛壢戝妛
戝妛徯夘 島嵗丒巤愝 擖帋忣曬 嫵堢丒尋媶 嶻妛楢実 崙嵺楢実 妛惗惗妶 晬懏昦堾
 

帬夑堛壢戝妛TOP > 嫵堢丒尋媶 > 嵟怴尋媶榑暥偺徯夘

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嵟怴尋媶榑暥偺徯夘
2017擭3寧7擔 峏怴
Shiraishi K, Okada Y, Takahashi A, Kamatani Y, Momozawa Y, Ashikawa K, Kunitoh H, Matsumoto S, Takano A, Shimizu K, Goto A, Tsuta K, Watanabe S, Ohe Y, Watanabe Y, Goto Y, Nokihara H, Furuta K, Yoshida A, Goto K, Hishida T, Tsuboi M, Tsuchihara K, Miyagi Y, Nakayama H, Yokose T, Tanaka K, Nagashima T, Ohtaki Y, Maeda D, Imai K, Minamiya Y, Sakamoto H, Saito A, ShimadaY, Sunami K, Saito M Inazawa J, Nakamura Y, Yoshida T, Yokota J, Matsuda F, Matsuo K, Daigo Y, Kubo M, Kohno T.
Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.

Nature Communications 2016;7:12451. Nature Communications 2016;7:12451. PMID: 27501781


擔杮恖偵懡偄EGFR曄堎傪帩偮攛態偑傫偺滊傝傗偡偝傪寛傔傞堚揱巕椞堟敪尒
乗柶塽傪巌傞HLA堚揱巕側偳6堚揱巕椞堟偑娭梌偡傞偙偲傪夝柧乗

乮僆乕僟乕儊僀僪堛椕幚尰壔僾儘僕僃僋僩乮帬夑堛戝昦堾傪娷傓12堛椕婡娭乯帋椏傪梡偄偨尋媶乯


丂悽奅偺攛偑傫巰朣悢偼慡偑傫巰偺栺17%傪愯傔嵟懡偱偁傝丄梊屻偼晄椙偱偁傞丅偦偺拞偱EGFR堚揱巕曄堎梲惈攛態偑傫偼擔杮恖傪娷傓傾僕傾恖偵懡偄孹岦偑偁傞丅

丂変乆偼丄擔杮恖偺攛態偑傫姵幰乮EGFR曄堎梲惈偑傫3,173椺丄EGFR曄堎堿惈偑傫3,694椺乯偲偑傫偵滊姵偟偰偄側偄廤抍乮15,158椺乯偺僒儞僾儖傪梡偄偰崅懍戝検僞僀僺儞僌僔僗僥儉偵傛傝70枩屄偺堚揱巕懡宆乮SNP乯偺僎僲儉儚僀僪娭楢夝愅傪峴偄丄EGFR曄堎梲惈偺攛態偑傫偺敪徢偵娭傢傞6偮偺堚揱巕椞堟傪摨掕偟偨丅偦偺堦偮偱偁傞柶塽墳摎偺屄恖嵎偺尨場偲側傞HLA僋儔僗II堚揱巕嶻暔偱偁傞HLA-DPB1僞儞僷僋幙偺57斣栚偺傾儈僲巁抲姺傪婲偙偡懡宆偼EGFR曄堎梲惈攛態偑傫偺滊姵惈傪寛傔傞場巕偺傂偲偮偲峫偊傜傟偨丅偙傟傜偺寢壥偼丄EGFR曄堎傪婲偙偟偨嵶朎偵懳偡傞峈庮釃柶塽墳摎偺屄恖嵎偑丄EGFR曄堎梲惈攛態偑傫傊偺滊傝傗偡偝偵娭梌偡傞壜擻惈傪帵嵈偟偰偄傞丅

丂崱屻丄偙傟傜偺堚揱慺場偲娐嫬梫場傪慻傒崌傢偣傞偙偲偱丄攛態偑傫偺敪徢儕僗僋恌抐朄傗怴偨側帯椕栻偺奐敪偵婑梌偡傞偙偲偑婜懸偝傟傞丅


暥愑丂丂椪彴庮釃妛島嵗丒庮釃撪壢丒庮釃僙儞僞乕丂丂戠岉丂栱懢榊

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寣埑偲慡塰梴娭楢夝愅
僙儃僼儖儔儞偼妶惈巁慺偵傛傞怱嬝彎奞傪梷惂偟偰嫊寣嵞燇棳彎奞偐傜怱憻傪曐岇偡傞
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寣塼惗壔妛抣傪婯掕偡傞46堚揱巕傪摨掕
Transient Receptor Potential Canonical 僠儍僱儖傪捠傞Ca2+偺棳擖偑怱嬝偺僇儖僔僂儉僷儔僪僢僋僗彎奞偺敪惗偵娭傢偭偰偄傞
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扨堦僾儔僢僩僼僅乕儉忋偵恌抐栻偲帯椕栻傪搵嵹偟偨挻暘巕僫僲僉儍儕傾偵傛傞壜帇壔僪儔僢僌僨儕僶儕乕偺丄鋁娻儌僨儖傪梡偄偨昡壙
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峈Dickkopf-1 (DKK1)峈懱偼娻嵶朎偐傜暘斿偝傟偨DKK1僞儞僷僋婡擻傪拞榓偟偰娻嵶朎偵傾億僩乕僔僗傪桿摫偡傞乛CDCA5僞儞僷僋桼棃偺嵶朎枌摟夁惈儁僾僠僪偼ERK僉僫乕僛偵傛傞CDCA5偺儕儞巁壔傪慖戰揑偵慾奞偟娻嵶朎偺憹怋傪梷惂偡傞
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The Pharmacology of Nitric Oxide in the Peripheral Nervous System of Blood Vessels.
Conserved role of nanos proteins in germ cell development.
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