2010擭11寧8擔
峏怴 |
Sato N, Koinuma J, Fujita M, Hosokawa M, Ito T, Tsuchiya E, Kondo S, Nakamura Y, Daigo Y* |
Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.** |
Clin Cancer Res. 2010;16:226-39. 丂 PMID: 20028748 |
AKT1僔僌僫儖偵偍偄偰攛娻丒怘摴娻偺敪惗偲埆惈壔偵娭傢傞怴婯恌抐丒帯椕昗揑暘巕傪摨掕 |
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Sato N, Koinuma J, Ito T, Tsuchiya E, Kondo S, Nakamura Y, Daigo Y* |
Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis. |
Genes Chromosomes Cancer. 2010;49:353-67 丂 PMID: 20095038 |
TSC1僔僌僫儖偵偍偄偰攛娻偺敪惗偲埆惈壔偵娭傢傞怴婯恌抐丒帯椕昗揑暘巕傪摨掕 |
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乮*Corresponding author丄**暷崙娻妛夛(AACR) 99th Annual Meeting, Scholar-In-Training Awards庴徿尋媶乯 |
亂梫巪亃
攛娻丒怘摴娻偵偍偗傞俀偮偺oncoprotein偑怐傝側偡怴偟偄僔僌僫儖揱払宱楬傪夝柧丅偦偺帯椕昗揑偲偟偰偺壜擻惈偲梊屻梊應僶僀僆儅乕僇乕偲偟偰偺桳梡惈傪帵偟偨丅
120徢椺偺僸僩攛娻丄怘摴娻慻怐専懱偲27,648堚揱巕傪栐梾偡傞cDNA儅僀僋儘傾儗僀傪梡偄偨僎僲儉儚僀僪側堚揱巕敪尰忣曬夝愅傪峴偄丄娻慻怐偱崅儗儀儖偵敪尰偟丄惓忢憻婍偱偼惛憙埲奜偵敪尰傪擣傔側偄娻惛憙峈尨乮cancer-testis antigen乯偱偁傝丄娻嵶朎偺憹怋丒惗懚偵娭傢傞oncoprotein偱偁傞WDHD1 (WD repeat and high-mobility group box DNA binding protein 1)偍傛傃TBC1D7 (TBC1 domain family, member 7)傪摨掕偟偨丅撈帺偵奐敪偟偨攛娻260椺丄怘摴娻280椺偐傜側傞慻怐儅僀僋儘傾儗僀偵傛傞夝愅偱偼丄WDHD1傕偟偔偼TBC1D7梲惈徢椺偼堿惈徢椺偵斾傋偰桳堄偵崻帯揑奜壢庤弍屻偺梊屻偑晄椙偱偁偭偨丅傑偨偦傟偧傟偺敪尰傪摿堎揑偵慾奞偡傞siRNA傪娻嵶朎姅偵摫擖偡傞偲嵶朎憹怋偑挊柧偵梷惂偝傟偨丅TBC1D7僞儞僷僋偺娻嵶朎撪偱偺埨掕惈偼丄柶塽捑崀朄偱摨掕偟偨TBC1D7偵寢崌偡傞僞儞僷僋偱偁傞TSC1 (Tuberous sclerosis complex)偲偺憡屳嶌梡偵傛傝堐帩偝傟偰偍傝丄偙偺僞儞僷僋娫寢崌傪慾奞偡傞嵶朎枌摟夁惈儁僾僠僪偺扴娻儅僂僗傊偺搳梌幚尡偱偼丄娻嵶朎偺憹怋梷惂偑妋擣偝傟偨丅堦曽丄WDHD1僞儞僷僋偼AKT1 (v-akt murine thymoma viral oncogene homolog 1)僉僫乕僛偵傛傝儕儞巁壔傪庴偗偰埨掕壔偟偰偄傞偙偲偑柧傜偐偲側偭偨丅
崱夞偺抦尒偼丄娻偺恌抐帯椕昗揑偲偟偰摨掕偟偨oncoprotein偑丄娻嵶朎撪偱妶惈壔偟偨忬懺偱懡嵤側娻壔僔僌僫儖僇僗働乕僪偺堦梼傪扴偆偙偲傪柧傜偐偵偟偰偍傝丄娻偺暘巕昦懺偵婎偯偄偨帯椕愴棯偺奐敪尋媶偵婑梌偡傞偙偲偑婜懸偝傟傞丅
暥愑丂憤崌偑傫帯椕妛島嵗丒庮釃撪壢丂戠岉丂栱懢榊 |