| 2011擭9寧12擔
峏怴 |
| Miki D, Kubo M, Takahashi A, Yoon KA, Kim J, Lee GK, Zo Jl, Lee JS, Hosono N, Morizono T, Tsunoda T, Kamatani N, Chayama K, Takahashi T, Inazawa J, Nakamura Y, Daigo Y*.. |
| Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. **,*** |
| Nature Genetics 2010;42:893-6. 丂 PMID: 20871597 |
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攛偑傫偺敪徢偵娭楢偡傞堚揱巕傪摨掕
亅攛偑傫敪徢偵俀偮偺偑傫娭楢堚揱巕乮TERT丄TP63乯偑娭學偡傞偙偲傪夝柧亅
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乮*Corresponding author丄**僆乕僟乕儊僀僪堛椕幚尰壔僾儘僕僃僋僩乮帬夑堛戝昦堾傪娷傓12堛椕婡娭乯帋椏傪梡偄偨尋媶丄***2011擭搙擔杮娻妛夛彠椼徿庴徿尋媶乯
丂攛偑傫偼悽奅揑偵丄偑傫偺巰朣偺尨場偲偟偰嵟傕昿搙偑崅偔丄偦偺敪惗棪偼搶傾僕傾偍傛傃墷暷彅崙偱憹壛偟偰偄傞丅変乆偼丄擔杮恖偲娯崙恖偺攛態偑傫姵幰2,098恖偲堦斒廤抍11,048恖偺僒儞僾儖傪梡偄偰崅懍戝検僞僀僺儞僌僔僗僥儉偵傛傝僎僲儉儚僀僪娭楢夝愅傪峴偄丄攛態偑傫偺敪徢偵娭傢傞2偮偺堚揱巕嵗埵偲偟偰TERT堚揱巕(rs2736100, combined P = 2.91 亊 10-11)偍傛傃TP63(p63)堚揱巕(rs10937405, combined P = 7.26 亊 10-12)傪摨掕偟偨丅TERT堚揱巕偺儕僗僋懡宆傪帩偮恖偱偼丄1.27攞丄TP63堚揱巕偺儕僗僋懡宆傪帩偮恖偱偼丄1.31攞丄攛態偑傫偺儕僗僋偑崅偔側偭偰偍傝丄偝傜偵丄2偮偺儕僗僋懡宆傪摨帪偵帩偮応崌偺攛態偑傫偺儕僗僋偼4.26攞偱偁偭偨丅TERT堚揱巕偐傜嶌傜傟傞抈敀幙偼丄愼怓懱枛抂(僥儘儊傾)偺斀暅攝楍傪怢偽偡峺慺偱偁傝丄偑傫嵶朎側偳偱妶惈壔偟偰嵶朎偺晄巰壔偵娭梌偡傞丅堦曽丄TP63堚揱巕偼丄偑傫梷惂堚揱巕TP53(p53)偲峔憿揑偵椶帡偟偨抈敀幙傪僐乕僪偡傞堚揱巕偱丄偦偺偑傫梷惂堚揱巕偲偟偰偺婡擻偑帵偝傟偰偄傞丅偙傟傜偺寢壥偼丄偑傫梷惂堚揱巕TP63偲偑傫嵶朎偺惗懚偵傕偐偐傢傞TERT偺堚揱巕懡宆偑攛態偑傫偺敪徢偵嫮偔娭梌偡傞偙偲傪帵嵈偟偰偍傝丄攛偑傫偺敪徢婡峔偺夝柧偺傒側傜偢丄崱屻丄攛態偑傫偺帯椕朄傗敪徢儕僗僋恌抐朄偺奐敪偵峷專偡傞傕偺偲婜懸偝傟傞丅
暥愑丂丂憤崌偑傫帯椕妛島嵗丒庮釃撪壢丂丂戠岉丂栱懢榊
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