2010擭12寧14擔
峏怴 |
Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M,丂Fujita H, Grarup N, Cauchi S, Ng DP, Ma RC, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR,Jorgensen T, Lauritzen T, Sandbak A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JC, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwagi A, Kawamori R, Kasuga M, Froguel P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T. |
A genome-wide association study in the Japanese population identifies Susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. |
Nat Genet. 2010 Oct;42(10):864-8.丂PMID: 20818381 |
僎僲儉儚僀僪憡娭尋媶偵傛傞擔杮恖2宆摐擜昦敪徢堚揱巕UBE2E2丄C2CD4A-C2CD4B偺摨掕 |
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亂梫巪亃
摐擜昦姵幰偲懳徠幰偺慡堚揱巕偺459,359儢強偺SNP傪3抜奒偺働乕僗丒僐儞僩儘乕儖偱夝愅偟乮1st 摐擜昦 4,470恖 vs. 懳徠3,071恖, 2nd 2,886恖 vs. 3,087恖, 3rd 3,622恖 vs. 2,356恖乯丄愼怓懱 3斣偺UBE2E2堚揱巕丄 愼怓懱15斣偺C2CD4A-C2CD4B堚揱巕偑擔杮恖俀宆摐擜昦偲娭學偺偁傞偙偲傪敪尒偟偨丅偙偺偆偪丄UBE2E2堚揱巕偱偼丄墫婎攝楍偑懳徠幰偲堎側傞偲摐擜昦敪徢偺婋尟偑1.2攞崅偔側傞偲悇掕偝傟丄擔杮恖姵幰偺15%偑偙偺僞僀僾偲峫偊傜傟傞丅
偝傜偵丄奜崙恖偵偍偗傞UBE2E2堚揱巕偺娭梌傪挷傋偨偲偙傠丄娯崙恖傗崄峘恖側偳偱偼摨條偺娭學偑擣傔傜傟偨偑丄僼儔儞僗恖傗僨儞儅乕僋恖偱偼摐擜昦偲娭楢偑側偐偭偨丅搶梞恖偼丄墷暷恖偺傛偆偵柧敀側旍枮偱側偔偰傕摐擜昦傪敪徢偡傞恖偑懡偔丄僀儞僗儕儞暘斿検偑墷暷恖偺敿暘偟偐側偄偙偲偑抦傜傟偰偍傝丄UBE2E2堚揱巕偼僀儞僗儕儞暘斿晄慡偵娭傢傞壜擻惈偑峫偊傜傟傞丅
暥愑丂撪壢妛島嵗乮摐擜昦撪暘斿丒恡憻丒恄宱乯慜愳丂憦 |
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