2010擭3寧25擔
峏怴 |
Takashi Uzu, Yasuo Kida, Nobuo Shirahashi, Tamaki Harada, Atsushi Yamauchi,
Makoto Nomura, Keiji Isshiki,Shin-ichi Araki, Toshiro Sugimoto, Daisuke Koya,
Masakazu Haneda, Atsunori Kashiwagi, and Ryuichi Kikkawa |
Cerebral Microvascular Disease Predicts Renal Failure
in Type 2 Diabetes |
Journal of the American Society of Nephrology(in press) |
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擼彫寣娗忈奞偼恡晄慡偺婋尟場巕偱偁傞 |
亂梫巪亃
俀宆摐擜昦姵幰偵偍偄偰丄抈敀擜傪掓偝偢偵枛婜恡晄慡偵帄傞徢椺偑彮側偐傜偢懚嵼偡傞丅恡婡擻掅壓偲恡撪偺寣娗掞峈槾恑偺娭楢偑曬崘偝傟偰偄傞偙偲傛傝丄旝彫寣娗昦曄偑恡婡擻掅壓偵婑梌偟偰偄傞偙偲偑嫮偔帵嵈偝傟傞丅 偟偐偟丄恡撪偺旝彫寣娗昦曄偺昡壙朄偼妋棫偟偰偄側偄丅傑偨丄枬惈恡憻昦乮CKD乯偑怱寣娗昦乮CVD乯偺婋尟場巕偱偁傞偙偲偼柧妋偵偝傟偰偄傞偑丄CVD偺CKD偵懳偡傞娭梌偼柧傜偐偱側偄丅
偦偙偱丄恡奜偺旝彫寣娗昦曄偱偁傞柍徢岓惈擼峓嵡乮SCI乯偺懚嵼偲恡婡擻掅壓偺娭楢偵偮偄偰専摙偟偨丅1995擭1寧偐傜2000擭12寧傑偱偵丄寣摐僐儞僩儘乕儖傑偨偼崌暪徢惛嵏偺栚揑偵偰擖堾偟偨姵幰傪懳徾偲偟偨丅帩懕惈抈敀擜丄恡婡擻掅壓乮寣惔Cr抝惈:>1.5mg/dl丄彈惈>1.3mg/dl乯怱寣娗崌暪徢偺婛墲偑桳傞傕偺偼懳徾偐傜彍奜偟偨丅
摢晹MRI偵偰柍徢岓惈擼峓嵡偺昡壙屻丄巰朣傑偨偼恡巰傪侾師昡壙崁栚丄寣惔Cr偺攞壔丄悇掕GFR偺掅壓丄恡徢僗僥乕僕偺恑揥傪俀師昡壙崁栚偲偟偰慜岦偒偵捛愓挷嵏傪峴偭偨丅捛愓壜擻偱偁偭偨608椺拞丄177椺偑乮SCI乯傪桳偟偰偄偨丅暯嬒7.5擭偺娤嶡婜娫拞丄SCI孮偺34偍傛傃旕SCI孮偺24椺偑侾師僄儞僪億僀儞僩偵帄傝丄SCI偺懚嵼偼巰朣丒恡巰偺撈棫偟偨婋尟場巕偱偁偭偨 (HR, 2.44; 95% CI, 1.36-4.38)丅
偝傜偵丄SCI偺懚嵼偼丄寣惔Cr偺攞壔偵偮偄偰傕撈棫偟偨婋尟場巕偲偟偰摨掕偝傟(HR, 4.79; 95% CI, 2.72-8.46)丄SCI孮偵偍偗傞悇掕GFR偺掅壓懍搙偼旕SCI孮偵斾偟槾恑偟偰偄偨丅偟偐偟丄恡徢僗僥乕僕偺恑揥偵娭偡傞撈棫場巕偲偟偰丄SCI偺懚嵼偺娭梌偼摨掕偝傟側偐偭偨丅
埲忋傛傝丄俀宆摐擜昦姵幰偵偍偄偰擼偺彫寣娗忈奞偑恡婡擻掅壓偺婋尟場巕偱偁傞偙偲偑柧傜偐偲側偭偨丅
暥愑丂撪壢妛島嵗丂塅捗丂婱 |
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