Kawakami T, Okamoto K, Ogawa O, Okada Y. |
XIST unmethylated DNA fragments in male-derived plasma as a tumor marker for testicular cancer. |
LANCET 2004;363:40-42.
PMID: 14723995
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X愼怓懱晄妶壔堚揱巕乮XIST乯旕儊僠儖壔DNA 偵傛傞惛憙娻偺恌抐 |
亂梫巪亃 惛憙庮釃偺敪惗昿搙偼寛偟偰崅偄傕偺偱偼側偄偑丄俀侽-俁侽嵨戜偺惵擭抝巕偵敪惗偡傞埆惈庮釃偲偟偰偼嵟傕昿搙偺崅偄傕偺偱偁傞丅壔妛椕朄偺恑曕偵傛傝揮堏惈惛憙庮釃姵幰偵偍偄偰傕80%埲忋偺帯桙棪偑摼傜傟傞傛偆偵側偭偰偒偨丅偟偐偟丄21悽婭偵擖偭偰傕偝傑偞傑側宍偱惛憙庮釃偺恌抐偺抶傟偲偦傟偵傛傞斶寑偑懚嵼偡傞偙偲偑巜揈偝傟偰偄傞乮LANCET 2002)丅偙偆偄偭偨惛憙庮釃傪庢傝姫偔攚宨傪峫偊傞偲偒丄摿堎惈偺崅偄惛憙庮釃儅乕僇乕傪扵嶕偡傞偙偲偼嬌傔偰廳梫側壽戣偲峫偊傜傟傞丅
崱夞傢傟傢傟偺僌儖乕僾偼廬棃偺屌宍娻偺曬崘偲偼堎側傞旕儊僠儖壔偲偄偆惛憙庮釃偵摿挜揑側僄僺僕僃僱僥僀僢僋僗偺摿惈傪媡偵棙梡偟丄摿堎揑DNA庮釃儅乕僇乕偲偟偰墳梡偱偒傞壜擻惈傪帵偟偨丅彈惈偵偍偄偰偼俀屄偁傞偆偪偺侾屄偺X愼怓懱偼晄妶壔傪庴偗丄抝惈偵偍偄偰偼妶惈宆X愼怓懱偑侾屄偺傒懚嵼偡傞丅偙偺X愼怓懱偺晄妶壔婡峔傪惂屼偡傞堚揱巕偲偟偰丄XIST堚揱巕乮X愼怓懱晄妶壔堚揱巕乯偑抦傜傟丄杮棃彈惈偵偺傒敪尰偑傒傜傟傞丅偙偺XIST堚揱巕偺敪尰惂屼婡峔偼儊僠儖壔偵傛偭偰偄傞丅偡側傢偪X愼怓懱晄妶壔堚揱巕乮XIST乯偺旕儊僠儖壔DNA偼彈惈偵偟偐懚嵼偣偢丄抝惈偺懱嵶朎偵偼懚嵼偟側偄傕偺偱偁傞丅
傢傟傢傟偼杮棃彈惈偵偟偐懚嵼偟側偄X愼怓懱晄妶壔堚揱巕乮XIST乯偺旕儊僠儖壔DNA偑僸僩惛憙庮釃慻怐堚揱巕偵峆忢揑偵懚嵼偡傞偙偲傪帵偟偨丅偝傜偵X愼怓懱晄妶壔堚揱巕乮XIST乯偺旕儊僠儖壔DNA抐曅偑惛憙庮釃姵幰偺寣惔偱専弌偝傟傞偙偲傪帵偟偨丅偙偺偙偲偼抝惈姵幰寣惔偵偍偄偰X愼怓懱晄妶壔堚揱巕乮XIST乯偺旕儊僠儖壔DNA抐曅偑専弌偝傟傟偽惛憙庮釃偺懚嵼偑帵嵈偝傟丄怴偨側庮釃儅乕僇乕偲偟偰偺堄媊偑偁傞偲峫偊傜傟傞丅
杮曬崘偼悽奅偱弶傔偰DNA偺旕儊僠儖壔抐曅傪庮釃儅乕僇乕偲偟偰墳梡偱偒傞壜擻惈傪帵嵈偟偨榑暥偱偁傝丄杮棃彈惈偵偟偐懚嵼偟側偄DNA抐曅傪庮釃儅乕僇乕偲偟偰梡偄傞偲偄偆儐僯乕僋側敪憐偐傜摼傜傟偨惉壥偱偁傞丅
暥愑丂斿擜婍壢妛島嵗 壀杮丂孿惗 |