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崙棫戝妛朄恖丗帬夑堛壢戝妛
戝妛徯夘 島嵗丒巤愝 擖帋忣曬 嫵堢丒尋媶 嶻妛楢実 崙嵺楢実 妛惗惗妶 晬懏昦堾

帬夑堛壢戝妛TOP > 嫵堢丒尋媶 > 嵟怴尋媶榑暥偺徯夘 > 偙傟傑偱偺徯夘榑暥

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嵟怴尋媶榑暥偺徯夘
2013擭5寧7擔 峏怴
Tzoulaki I, Patel CJ, Okamura T, Chan Q, Brown IJ, Miura K, Ueshima H, Zhao L, Van Horn L, Daviglus ML, Stamler J, Butte AJ, Ioannidis JP, Elliott P.
A nutrient-wide association study on blood pressure.

Circulation. 2012 Nov 20;126(21):2456-64.丂 PMID: 23093587


寣埑偲慡塰梴娭楢夝愅

丂宯摑揑側曃傝偺側偄塰梴慺偲寣埑偺娭楢惈傪専摙偡傞偨傔偵慡塰梴娭楢夝愅(nutrient-wide approach study)傪幚巤偟偨丅

丂塰梴偲寣埑偵娭偡傞崙嵺嫟摨尋媶偱偁傞INTERMAP尋媶(International Study of Macro/Micronutrients and Blood Pressure)偵嶲壛偟偨40-59嵨偺4,680恖傪懳徾偲偟偰丆柍嶌堊偵敿暘偵暘偗丆偦傟偧傟専摙梡僨乕僞僙僢僩偲僥僗僩梡僨乕僞僙僢僩偲偟偨丅
丂奜晹懨摉惈偺専摙偵偼暷崙崙柉寬峃丒塰梴挷嵏(US National Health and Nutrition Examination Survey (NHANES))偺4婜乮1999-2000, 2001-2002, 2003-2004, 2005-2006乯偺僨乕僞傪梡偄偨丅INTERMAP尋媶丆NHANES偼偄偢傟傕墶抐尋媶偱偁傞丅
丂専摙梡僨乕僞僙僢僩傪梡偄偰丆廳夞婣暘愅偵偰82庬椶偺塰梴慺偍傛傃3庬椶偺擜拞揹夝幙偲廂弅婜丆奼挘婜寣埑偺娭楢傪専摙偟丆摑寁揑偵桳堄側娭楢偑偁偭偨塰梴慺偵偮偄偰偼丆INTERMAP偺僥僗僩梡僨乕僞僙僢僩傪梡偄偰撪晹懨摉惈傪丆NHANES僨乕僞傪梡偄偰奜晹懨摉惈傪専摙偟偨(婾梲惈棪偼専摙梡僨乕僞僙僢僩偱5%枹枮偲偟丆撪晹懨摉惈丆奜晹懨摉惈偺専摙偱偼P亙0.05傪桳堄偲偟偨)丅
丂懨摉惈傪専摙偟偨塰梴慺偱偼丆傾儖僐乕儖偲擜拞Na/K斾偼廂弅婜寣埑偲惓偺娭楢傪帵偟丆怘帠惈偺儕儞丆儅僌僱僔僂儉丆揝丆價僞儈儞B1丆梩巁丆價僞儈儞B2偼廂弅婜寣埑偲晧偺娭楢傪帵偟偨丅偝傜偵怘帠惈偺梩巁偲價僞儈儞B2偼奼挘婜寣埑偲傕晧偺娭楢傪帵偟偨丅NHANES僨乕僞偵偍偄偰丆廂弅婜寣埑偼丆塰梴慺偺愛庢検1SD憹壛偛偲偵0.97mmHg(儕儞)偐傜0.39mmHg(梩巁)傑偱偺掅壓傪帵偟偨丅怘帠偵壛偊偰僒僾儕儊儞僩偐傜偺塰梴慺愛庢忬嫷偲寣埑偺娭楢傪専摙偟偨偲偙傠丆梩巁丆價僞儈儞B1丆價僞儈儞B2偲偺娭楢偼庛偔側偭偨偑丆摑寁揑偵桳堄側娭楢傪帵偟偨懠偺塰梴慺偵偮偄偰偼奣偹摨條偺寢壥傪摼偨丅

丂 偙傟傑偱庛偄娭楢偟偐帵偝傟偰偙側偐偭偨價僞儈儞B孮偲寣埑偺娫偵桳堄側晧偺娭楢傪擣傔偨丅杮夝愅偵傛傝丆宯摑揑側曃傝偺側偄塰梴慺偲寣埑偺娭楢傪昡壙偱偒偨偲偄偊傞丅

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