| 2012擭3寧21擔 峏怴 |
| Morino K, Petersen KF, Sono S, Choi CS, Samuel VT, Lin A, Gallo A, Zhao H, Kashiwagi A,
Goldberg IJ, Wang H, Eckel RH, Maegawa H, Shulman GI |
| Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin Resistant Offspring of Parents with Type 2 Diabetes |
| Diabetes 2012 in press (April) 丂 PMID: 22368174 |
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| 僀儞僗儕儞掞峈惈姵幰偵娤嶡偝傟傞崪奿嬝儕億僾儘僥僀儞儕僷乕僛妶惈掅壓偑儈僩僐儞僪儕傾婡擻傪掅壓偝偣傞 |
丂摐擜昦敪徢憗婜偵偼崪奿嬝偵偍偗傞僀儞僗儕儞偺嶌梡晄慡乮僀儞僗儕儞掞峈惈乯偑娤嶡偝傟傞偑丄偦偺儊僇僯僘儉偲偟偰丄崪奿嬝嵶朎撪偵崅帀朾怘傗塣摦晄懌偲偄偭偨娐嫬場巕偵傛偭偰堎強惈偵帀朾偑拁愊偡傞帠偵傛傝僀儞僗儕儞嵶朎撪忣曬揱払偑忈奞偝傟傞壜擻惈偑帵嵈偝傟偰偄傞丅堎強惈帀朾拁愊偺尨場偲偟偰旍枮傗塣摦晄懌偺傒側傜偢儈僩僐儞僪儕傾偺婡擻晄慡偺懚嵼傪曬崘偝傟偰偄傞丅杮尋媶偱偼丄僀儞僗儕儞掞峈惈旐専幰偱娤嶡偝傟傞崪奿嬝儈僩僐儞僪儕傾婡擻掅壓偺尨場傪扵媮偡傞栚揑偱丄僀儞僗儕儞掞峈惈旐専幰偺嬝惗専僒儞僾儖偱DNA micro array傪峴偄丄mRNA敪尰傪寬忢幰偲斾妑偟偨丅偦偺寢壥丄250堚揱巕偵桳堄側嵎傪擣傔偨丅帀朾巁巁壔偺堚揱巕孮偼僀儞僗儕儞掞峈惈旐専幰偱桳堄偵掅壓偟偰偄偨丅偦偙偱丄崪奿嬝攟梴嵶朎傪梡偄偰忋婰250堚揱巕偵懳偟偰RNAi偵傛傞堚揱巕knock down偵傛傞栐梾揑側専嶕傪峴偄丄怴婯儈僩僐儞僪儕傾挷愡場巕傪扵嶕偟偨寢壥丄Lipoprotein Lipase (LPL)傪摨掕偟偨丅LPL敪尰偼僀儞僗儕儞掞峈惈旐専幰偱mRNA丄僞儞僷僋敪尰偲傕偵桳堄偵掅壓偟偰偍傝丄儈僩僐儞僪儕傾枾搙偲LPL敪尰偑憡娭偡傞帠傕妋擣偝傟偨丅LPL偑2宆摐擜昦偱掅壓偡傞帠偼屆偔偐傜抦傜傟偰偍傝丄崅帀寣徢偺尨場偺堦偮偲峫偊傜傟傞偑丄変乆偺尋媶寢壥偼LPL掅壓偑儈僩僐儞僪儕傾婡擻堎忢偺尨場偱偁傞壜擻惈傪帵嵈偟偰偄傞揰偵偍偄偰怴偨側敪尒偱偁傞丅攟梴嵶朎偵偍偄偰丄LPL RNAi偵傛傞堚揱巕僲僢僋僟僂儞偼儈僩僐儞僪儕傾枾搙丒抈敀幙丒巁壔擻傪掅壓偝偣偨丅嵶朎撪傊偺帀朾棳擖帺懱偑儈僩僐儞僪儕傾傪挷愡偟偰偄傞偲峫偊丄帀朾庢傝崬傒偺廳梫側場巕偱偁傞CD36乮fatty acid transporter乯傪RNAi偱張棟偟偨偲偙傠丄LPL摨條偵儈僩僐儞僪儕傾傪尭彮偝偣偨丅変乆偼PPARD偑崪奿嬝嵶朎撪偺帀朾棳擖僙儞僒乕偱偁傞偲峫偊丄PPARD傕RNAi偱張棟偟偨偲偙傠儈僩僐儞僪儕傾偺尭彮偑妋擣偝傟偨丅
寢榑丗僀儞僗儕儞掞峈惈旐専幰偱娤嶡偝傟偨儈僩僐儞僪儕傾枾搙掅壓偺尨場偲偟偰LPL偺娭梌偑帵嵈偝傟偨丅LPL-CD36-PPARD宱楬偑崪奿嬝傊偺帀朾棳擖偺掱搙傪姶抦偟丄儈僩僐儞僪儕傾丒帀朾巁巁壔傪挷愡偟偰偄傞壜擻惈偑偁傞丅杮尋媶偼摐擜昦敪徢婡彉夝柧傗旍枮帯椕傊偺怴偨側傾僾儘乕僠傊偲敪揥偡傞壜擻惈偑偁傞丅
暥愑丂丂摐擜昦撪暘斿撪壢丂丂慜愳丂憦 |
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