Shigeo Yura, Hiroaki Itoh, Norimasa Sagawa, Hiroshi Yamamoto, Hiroaki Masuzaki, Kazuwa Nakao, Makoto Kawamura, Maki Takemura, Kazuyo Kakui, Yoshihiro Ogawa, Shingo Fujii |
Role of premature leptin surge in obesity resulting from intrauterine undernutrition. |
Cell Metabolism 2005;1(6):371-378
PMID: 16054086 |
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戀惗婜偵偍偗傞掅塰梴娐嫬偵婲場偡傞惉挿屻偺旍枮敪徢偵偼丄惉挿婜偺乽儗僾僠儞僒乕僕偺憗婜壔乿偑廳梫側栶妱傪偼偨偡 |
亂梫巪亃 墷暷偺愭恑崙偺傒側傜偢丄傢偑崙偵偍偄偰傕怘惗妶丄惗妶僗僞僀儖偺墷暷壔偵敽偄惗妶廗姷昦偺憹壛偑娕夁偱偒側偄幮夛栤戣偲側偭偰偄傑偡丅偲傝傢偗旍枮偼惗妶廗姷昦偺埆壔梫場偲偟偰廳梫偱偁傝丄偦偺敪徢婡彉偺夝柧偼堚揱慺場傗惗妶廗姷偺曄壔傪拞怱偵惛椡揑偵恑傔傜傟偰偄傑偡丅
嬤擭偺塽妛揑尋媶偐傜丄戞擇師悽奅戝愴慜屻偺婹夓傪擠怭拞偵宱尡偟偨曣恊偐傜弌惗偟偨帣偑丄惉恖屻偵旍枮傗惗妶廗姷昦傪崅棪偵堷偒婲偙偡偙偲偑柧傜偐偲側傝丄Developmental Origins of Health and Diseases乮DOHaD:惉挿夁掱偵偍偗傞塰梴忈奞傗娐嫬場巕偺嶌梡偵婲場偡傞幘姵偺敪惗乯偲偄偆奣擮偑採彞偝傟傞傛偆偵側傝傑偟偨丅偝傜偵2,500g枹枮偺掅弌惗懱廳帣偼惉恖屻偵旍枮敪徢棪偑崅偄偲偄偆塽妛曬崘傕偁傝傑偡丅
嬤擭杮朚偱偼憗婜嶻帣傗2500g枹枮偺掅弌惗懱廳帣偺妱崌偑憹壛偟丄庒擭彈惈偺憠偣婅朷傗晄婯懃側怘惗妶側偳傕偁偭偰丄惓婜嶻帣偵偍偄偰傕弌惗懱廳偺掅壓孹岦偑巜揈偝傟偰偄傑偡丅偦偺偨傔偙傟傜偺掅弌惗懱廳帣傗巕媨撪敪堢惂尷帣乮IUGR帣乯偑丄彨棃崅棪偵旍枮側偳偺惗妶廗姷昦傪敪徢偡傞壜擻惈偑婋湝偝傟傑偡丅
忋婰偺傛偆側塽妛揑僨乕僞偼嵟嬤偺摦暔幚尡偱傕棤晅偗傜傟偰棃傑偟偨偑丄偦偺嬶懱揑側婡彉偼傎偲傫偳夝柧偝傟偰偄傑偣傫偱偟偨丅
杮尋媶偱偼丄儅僂僗曣廱偵愛怘惂尷傪壛偊傞偙偲偱IUGR偺儌僨儖傪嶌惉偟丄惗傑傟偨怴惗巈偺惉挿屻偵崅帀朾怘傪晧壸偟偨偲偙傠丄惓忢懳徠孮偵斾傋偰桳堄偵旍枮搙偑槾恑偟傑偟偨丅偙偺儅僂僗儌僨儖偱偼丄怴惗巈婜偺catch-up婜乮IUGR帣偑惓忢帣偺懱廳偵捛偄偮偔帪婜乯偵堦抳偟偰旍枮惂屼儂儖儌儞偱偁傞儗僾僠儞嶻惗偺堦夁惈偺槾恑偺憗婜壔傪擣傔偨偨傔丄偙偺尰徾傪乽premature leptin surge;儗僾僠儞僒乕僕偺憗婜壔乿偲柤晅偗傑偟偨丅惓忢儅僂僗偺怴惗巈偵儗僾僠儞傪搳梌偟偰乽儗僾僠儞僒乕僕偺憗婜壔乿傪堷偒婲偙偟偨偲偙傠丄崅帀朾怘晧壸偵傛傝摨條偵旍枮偑壛懍偟偨偙偲偐傜丄偙偺尰徾偼旍枮偺DOHaD偵偍偄偰拞怱揑側栶妱傪壥偨偡偙偲偑憐掕偝傟傑偟偨丅偝傜偵乽儗僾僠儞僒乕僕偺憗婜壔乿偼丄儅僂僗帇彴壓晹偵偍偄偰儗僾僠儞偺姶庴惈傪掅壓偝偣丄偐偮Neuropeptide Y (NPY)偁傞偄偼Cocaine- and amphetamine-regulated transcript (CART)側偳僄僱儖僊乕戙幱挷愡傪巌傞恄宱僯儏乕儘儞偺敪払偵塭嬁傪媦傏偡偙偲偑柧傜偐偲側傝傑偟偨丅偙傟傜偺曄壔偼寢壥偲偟偰丄崅帀朾怘晧壸偵懳偡傞擬嶻惗偺忋徃傪梷惂偟丄旍枮傪壛懍偡傞偙偲傪夝柧偟傑偟偨丅杮尋媶偼丄戀惗婜偺掅塰梴偑惉挿屻偺崅帀朾怘側偳惗妶廗姷偵偲傕側偆旍枮敪徢偺儕僗僋場巕偲側傞婡彉傪丄悽奅偱弶傔偰嬶懱揑偵夝柧偟偨傕偺偱偡丅杮尋媶偵傛傝DOHaD偵傛傞旍枮偺婡彉偺堦抂偑夝柧偝傟偨偙偲偐傜丄崱屻偺梊杊偁傞偄偼帯椕愴棯傪奐敪偡傞抂弿偲側傞偙偲偑婜懸偝傟傑偡丅
暥愑丂奜壢妛島嵗丄嶳杮丂姲乮嫗搒戝妛偲偺嫟摨尋媶乯 |
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