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惗妶廗姷昦梊杊偺帇揰丗戝婯柾挿婜捛愓挷嵏 NIPPON DATA80 偺抦尒傛傝

帬夑堛壢戝妛暉巸曐寬堛妛島嵗丄
忋搰峅巏

嘥. 偼偠傔偵

丂弞娐婍幘姵婎慴挷嵏偼傎傏10擭偍偒偵丄傢偑崙偺弞娐婍幘姵偺摦岦傪攃埇偟偦偺懳嶔傪桳岠偵島偠傞偨傔偺婎慴帒椏傪摼傞栚揑偱幚巤偝傟偰偒偨丅偙傟偼丄崙柉塰梴挷嵏偺懳徾幰偱30嵨埲忋偵尷掕偟偰崙柉塰梴挷嵏偺崁栚偵捛壛偡傞宍偱幚巤偝傟偰偒偨丅挊幰傜偼丄1980擭偺弞娐婍幘姵婎慴挷嵏偑幚巤偝傟偰10擭傪宱夁偟偨抜奒偱丄擔杮弞娐婍娗棟尋媶嫤媍夛乮棟帠挿丂斞懞丂峌丂嶥杫堛壢戝妛柤梍嫵庼乯偺帠嬈偲偟偰丄1994擭偵傢偑崙偱弶傔偰丄峴惌偺抐柺挷嵏傪儀乕僗偵偟偰捛愓挷嵏偑峴傢傟傞偙偲偵側傝丄慡崙偺曐寬強偺嫤椡傪摼偰捛愓挷嵏傪幚巤偟偨丅尰嵼丄1990擭偺僐儂乕僩傕娷傔丄偦傟偧傟丄19擭丄10擭偺捛愓偑姰椆偟偨丅偙偙偱偼丄偦偺捛愓挷嵏偺幚巤宱夁偲偲傕偵摼傜傟偨抦尒傛傝丄惗妶廗姷昦偺梊杊偵偲偭偰廳梫側梫場偵偮偄偰弎傋傞丅

嘦. 崙柉偺戙昞偲側傞廤抍偺捛愓栚揑

丂杮尋媶偼崙柉傪戙昞偡傞廤抍偺捛愓挷嵏惉愌偱偁傞偙偲偲丄偦偺懳徾偺1980擭丄1990擭偼偦傟偧傟侾枩恖乮NIPPON DATA80乯丄8000恖(NIPPON DATA90)偲偄偆婯柾偺戝偒偝偵摿挜偑偁傞丅1994擭偵偼偠傔偰屻傠岦偒偵1980擭偺岤惗楯摥徣偺弞娐婍幘姵婎慴挷嵏傪捛愓挷嵏偲偟偰丄惗巰偺梊屻偲65嵨埲忋偺崅楊幰偵懳偡傞擔忢惗妶摦嶌擻椡乮ADL乯傪捛愓偡傞偙偲偲側偭偨乮恾侾乯丅
丂憤柋挕偵巜掕摑寁偺栚揑奜巊梡傪怽惪偟丄慡崙偺曐寬強傊挷嵏嫤椡偺埶棅傪峴偄丄抁婜娫偺娫偵僐儂乕僩尋媶偲偟偰偺惉棫偝偣傞偙偲偑偱偒偨丅弞娐婍幘姵丄娻偵傛傞巰朣偺婋尟場巕傗偦偺懠偺庡梫側巰場偺婋尟場巕傪専摙偱偒偨偲偄偆揰偑戝偒側惉壥偱偁偭偨1-4)丅
丂捛愓棪偼丄恾侾偵帵偟偨傛偆偵偦傟偧傟91亾丄97亾傪摼偨丅傑偨丄擔杮傪戙昞偡傞65嵨埲忋偺廤抍偺ADL傗惗妶偺幙偵偮偄偰偺忬嫷傪柧傜偐偵偡傞偙偲偑偱偒偨丅


恾1 NIPPON DATA偺尋媶僨僓僀儞偲宱夁

嘨. 寉徢崅寣埑偺廳梫惈

丂崅寣埑偺塭嬁傪専摙偡傞偨傔偵丄暷崙崅寣埑崌摨埾堳夛戞俇師曬崘彂偵偟偨偑偭偰丄寣埑抣偐傜俇孮偵懳徾幰傪嬫暘偟丄偦偺屻偺弞娐婍幘姵巰朣棪傪専摙偟偨丅昞侾偵偦偺寣埑嬫暘暿偺抝彈暿捛愓恖悢丄擭楊丄寣埑抣丄Body Mass Index (BMI, kg/m2)丄寣惔憤僐儗僗僥儘乕儖抣丄媔墝棪丄堸庰棪丄崀埑栻帯椕棪丄摍傪帵偟偨4)丅俇孮偼丄僌儖乕僾I偺帄揔寣埑孮乮廂弅婜寣埑<120mmHg, 奼挘婜寣埑 <80mmHg 乯偐傜VI孮偺廂弅婜寣埑 180mmHg 埲忋偁傞偄偼奼挘婜寣埑 110mmHg 埲忋偱偁傞乮昞侾乯丅抝惈偱偼丄寣埑嬫暘偑崅偔側傞傎偳丄擭楊丄寣埑抣丄BMI丄堸庰棪丄摐擜昦桳昦棪丄崀埑栻暈梡棪偼崅偐偭偨偑丄彈惈偱偼丄抝惈偲堎側傝寣惔憤僐儗僗僥儘乕儖抣偑崅偔丄堸庰棪偼崅偔側偐偭偨丅


昞1 寣埑嬫暘暿偺挷嵏奐巒帪強尒丄NIPPON DATA80, 1980擭丄擔杮崙柉偺儔儞僟儉僒儞僾儖

丂昞俀偵帵偟偨傕偺偼丄寣埑嬫暘暿偺捛愓恖擭丄巰朣悢丄擭楊挷惍憤巰朣棪丄擭楊挷惍弞娐婍幘姵巰朣棪丄擭楊挷惍怱幘姵巰朣棪丄擭楊挷惍擼懖拞巰朣棪偱偁傞4)丅廳搙崅寣埑孮VI偺恖悢偼俇孮偺拞偱偼懡偔側偐偭偨偑丄儕僗僋偑崅偔懡偔偺巰朣幰偑偱偨丅傑偨丄偦偺撪偺係0亾傪挻偊傞傕偺偑弞娐婍幘姵巰朣偱偁偭偨丅
丂廳徢偺崅寣埑偼弞娐婍幘姵偵懳偡傞憡懳婋尟搙偼崅偄偑乮昞俀乯丄偦偺傛偆側廳搙偺崅寣埑幰偼懡偔側偄乮昞侾乯丅媡偵寉徢偺崅寣埑幰偼偦偺恖悢傕懡偄丅偟偨偑偭偰丄寉徢崅寣埑IV孮偵傛傞擼懖拞夁忚巰朣傪寁嶼偡傞偲抝惈偱偼48%丄彈惈16%偵媦傫偩丅偡側傢偪丄寉徢傕娷傔偨崅寣埑懳嶔偑廳梫偱偁傝丄暷崙崅寣埑崌摨埾堳夛偑廂弅婜寣埑 120mmHg 傪挻偊傞傕偺丄偁傞偄偼奼挘婜寣埑 80mmHg 傪挻偊傞傕偺偱偁傝丄偐偮崅寣埑偱側偄傕偺傪崅寣埑梊旛孯偲偟偰偁偮偐偭偨偙偲偵傕偦偺堄枴偑偁傞5)丅


昞2 捛愓恖擭偍傛傃10枩恖擭偁偨傝偺擭楊挷惍巰朣棪丄寣埑嬫暘暿丄1980擭偐傜偺14擭娫偺捛愓挷嵏

嘩. 崅僐儗僗僥儘乕儖寣徢偲掅僐儗僗僥儘乕儖偺儕僗僋偺堄媊

丂NIPPON DATA80偼恾俀偵帵偡傛偆偵丄嫊寣惈怱幘姵偺儕僗僋偲偟偰偺寣惔憤僐儗僗僥儘乕儖偺堄媊傪柧妋偵偟偨3)丅傢偑崙偱偼嫊寣惈怱幘姵偼悽奅偺愭恑岺嬈崙偺拞偱偼傕偭偲傕掅偄崙偺堦偮偱偁傞偑丄寣惔憤僐儗僗僥儘乕儖抣偺忋徃偼嫊寣惈怱幘姵偵傛傞巰朣偺婋尟搙傪抜奒揑偵忋徃偝偣傞偙偲偼娫堘偄側偄丅


恾2 寣惔憤僐儗僗僥儘乕儖嬫暘暿偺姤摦柆幘姵巰朣儕僗僋丄抝惈4035恖14擭娫偺捛愓丄NIPPON DATA80

丂崅僐儗僗僥儘乕儖寣徢偲斀懳偺掅僐儗僗僥儘乕儖寣徢偺栤戣偵偮偄偰偼偳偆偱偁傠偆偐丅NIPPON DATA80偺惉愌偼丄僐儗僗僥儘乕儖抣偺掅偄廤抍偼憤巰朣棪偑崅偄偙偲偑柧傜偐偲側偭偨 3)丅偙偺尨場偼娻偵傛傞巰朣偑掅僐儗僗僥儘乕儖孮偵懡偄偙偲偵傛偭偨(恾俁)3)丅NIPPON DATA80偺惉愌傪堷梡偟偰丄扨弮偵寣惔憤僐儗僗僥儘乕儖抣傪壓偘傞偙偲偼婋尟偱偁傞偲偺榑媍偑偁傞偑丄変乆偼扨弮偵偦偺傛偆偵偼峫偊偰偄側偄丅偦傟偼丄掅僐儗僗僥儘乕儖孮偵娞憻幘姵偵傛傞巰朣偑懡偔丄娞幘姵偵傛傞巰朣傪彍偔偲掅僐儗僗僥儘乕儖偲娻偺娭楢惈偼徚幐偡傞偐傜偱偁傞3)丅偟偨偑偭偰丄偙偺栤戣偵偼偝傜側傞幚徹偑偄傞偑丄傢傟傢傟偼掅僐儗僗僥儘乕儖孮偵娻偵傛傞巰朣偑懡偄偙偲偼丄場壥偺媡揮偑惗偠偰偄傞壜擻惈偑傓偟傠戝偱偁傞偲峫偊偰偄傞3)丅
丂偟偐偟丄僗僋儕乕僯儞僌屻偺掅僐儗僗僥儘乕儖幰偵娻偑懡偔敪徢偟巰朣偡傞偙偲偵娫堘偄偼側偔丄掅僐儗僗僥儘乕儖幰偵偼塰梴忬嫷偺揰専偲偲傕偵丄娻偑懚嵼偟側偄偐偺拲堄怺偄娤嶡偑昁梫偱偁傞丅


恾3 寣惔憤僐儗僗僥儘乕儖嬫暘暿偺慡娻巰朣儕僗僋丄抝惈4035恖丄彈惈5181恖偺14擭娫偺捛愓丄NIPPON DATA80

嘪. 媔墝偺弞娐婍幘姵偍傛傃娻傊偺塭嬁

丂媔墝偑怱嬝峓嵡偺婋尟場巕偱偁傞偙偲偼丄傢偑崙偺塽妛挷嵏偱傕屆偔偐傜偟傜傟偰偄傞丅偟偐偟丄擼懖拞偺婋尟場巕偱偁傞偙偲傪帵偟偨惉愌偼朢偟偄6)丅NIPPON DATA80偼柧椖偵媔墝偺擼懖拞巰朣儕僗僋傪柧傜偐偵偟偨丅
丂媔墝偑娻偲偔偵攛偑傫偺婋尟場巕偱偁傞偙偲偼傛偔抦傜傟偰偄傞偑丄傢偑崙偱偼暯嶳偺僐儂乕僩尋媶埲棃丄懠偺僐儂乕僩尋媶偱摨條偺尋媶寢壥偼崱傑偱曬崘偝傟偰偄側偐偭偨丅偙偺揰偵偍偄偰傕丄NIPPON DATA80偼暯嶳偺抦尒傪嵞妋擣偟丄抝惈偺枅擔1敔媧偆媔墝幰偱偼攛偑傫巰朣偺儕僗僋偼旕媔墝幰偵斾偟偰6攞偱偁偭偨2)丅


恾4 媔墝偲攛娻巰朣棪偺娭楢偺嫮偝19擭偺捛愓丄NIPPON DATA80

嘫. ADL掅壓偵梌偊傞擼懖拞丄崪愜偺塭嬁

丂NIPPON DATA80,90偼捛愓帪偵65嵨埲忋弌夛偭偨惗懚幰偵偨偄偟偰丄ADL偲惗妶偺幙(QOL)傪挷嵏偟偨丅怮偨偒傝梊杊偺娤揰偐傜偡傞偲挻崅楊偵帄傜側偄帪婜偱偺ADL掅壓傪杊偖偙偲偑嵟傕廳梫偱偁傞偑丄NIPPON DATA偺惉愌偼丄ADL掅壓梫場偵偍偗傞擼懖拞偲崪愜偺廳傒傪柧傜偐偵偟偨7)丅偡側傢偪丄擼懖拞偵傛傞ADL掅壓偺恖岥婑梌婋尟搙乮ADL掅壓幰偺撪丄擼懖拞偵傛傞傕偺偑偳傟偩偗偐丄擼懖拞偑側偗傟偽ADL掅壓幰偼偳傟偩偗尭彮偡傞偐傪帵偡巜昗乯偑抝惈偱偼54%丄彈惈偱偼21.7%偱偁偭偨丅傑偨丄彈惈偺崪愜偵傛傞ADL掅壓偺恖岥婑梌婋尟搙偼丄30.4%偱偁偭偨丅偙偺偙偲傛傝丄ADL掅壓梊杊丄傂偄偰偼怮偨偒傝梊杊偵擼懖拞梊杊偑偄偐偵廳梫偱偁傞偐傪帵偟偨丅


恾5 抝彈暿偵傒偨ADL掅壓偵懳偡傞擼懖拞媦傃壔偟崪愜偺恖岥婑梌婋尟搙妱崌

嘮. 廔傢傝偵

丂崙柉傪戙昞偡傞廤抍摿惈傪桳偡傞NIPPON DATA80偼丄岤惗楯摥徣偑崙柉偺寬峃堐帩偲憹恑偺偨傔偵掕傔傛偆偲偟偰偄傞巤嶔偺婎慴帒椏偲側偭偨丅摿偵丄寬峃擔杮21偺婎慴帒椏偲偟偰偺棙梡壙抣偑戝偱偁偭偨丅杮僐儂乕僩尋媶偼丄寣埑偲弞娐婍幘姵丄媔墝丒堸庰偲弞娐婍幘姵傪偼偠傔偲偟偰丄旍枮搙丄寣摐抣丄寣惔憤僐儗僗僥儘乕儖抣摍偝傑偞傑側梫場偲丄憤巰朣丄弞娐婍幘姵傗偦偺懠偺巰場丄ADL丒QOL掅壓偲偺娭楢側偳偑暘愅壜擻側憤崌揑側僐儂乕僩尋媶偲側偭偨丅

暥專

  1. 忋搰峅巏乮尋媶斍傪戙昞偟偰乯丏戞31夞擔杮弞娐婍娗棟尋媶嫤媍夛憤夛婰榐丂摿暿曬崘丂1980擭弞娐婍幘姵婎慴挷嵏偺捛愓挷嵏乮NIPPON DATA乯丄擔弞嫤帍 31;231-237丄1997.
  2. 愳撿, 懠丏媔墝廗姷偺慡巰場丄偑傫丄攛偑傫巰朣傊偺塭嬁偵娭偡傞尋媶丗NIPPON DATA80.擔杮塹惗妛嶨帍 57:669-73,2003.
  3. Okamura T, et al. What cause of mortality can we predict by cholesterol screening in the Japanese general population? J Intern Med 253:169-80, 2003.
  4. NIPPON DATA80 Research Group. Impact of elevated blood pressure on mortalitynfrom all causes, cardiovascular diseases, heart diseases and stroke among Japanese: fourteen year follow-up of randomly selected population from Japanese: NIPPON DATA80. J Hum Hypertens 17:851-857, 2003.
  5. Chobanian AV, et al. Seventh report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure : the JNC 7 report. JAMA 289: 2560-72, 2003.
  6. 忋搰峅巏. 丂擼懖拞婋尟場巕偲偟偰偺媔墝丗丂擼寣娗忈奞乗椪彴偲尋媶偺嵟慜慄丄堛妛偺偁備傒丂暿嶜丄搶媀塸晇曇丄p35-39,丂堛帟栻弌斉丄搶嫗丄2001丅
  7. Hayakawa T, et al. Prevalence of impaired activities of daily living andnthe impact of stroke and lower limb fracture in elderly persons in Japan. CVD Prevention 3:187-194, 2000.